| Titre : | Estimation of the Relative Excess Risk Due to Interaction and Associated Confidence Bounds. (2009) |
| Auteurs : | David-B RICHARDSON ; Jay-S KAUFMAN |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 169, n° 6, 2009) |
| Pagination : | 756-760 |
| Langues: | Anglais |
| Mots-clés : | Estimation ; Intervalle confiance ; Facteur risque ; Epidémiologie ; Homme ; Risque relatif |
| Résumé : | [BDSP. Notice produite par INIST-CNRS tsIpR0xk. Diffusion soumise à autorisation]. The relative excess risk due to interaction (RERI) provides a useful metric of departure from additivity of effects on a relative risk scale. In this paper, the authors show that RERI is identical to the product term in a linear odds ratio or a linear relative risk model. SAS and STATA codes are provided for fitting a linear odds ratio model that directly parameterizes RERI. In addition, this paper presents a method for obtaining likelihood-based 95% confidence bound estimates for RERI. The authors show that likelihood-based confidence intervals may differ substantially from the asymptotic confidence interval estimates advocated by previous authors. The approach presented in this paper should facilitate estimation of RERI and associated likelihood-based confidence bounds, by using standard statistical packages. |

