Regression to the mean : what it is and how to dea... Catalogue en ligne

Titre :	Regression to the mean : what it is and how to deal with it. (2005)
Auteurs :	Adrian-G BARNETT ; Annette-J DOBSON ; Jolieke-C VAN DER POLS ; University of Queensland. School of Population Health. Herston Brisbane. AUS
Type de document :	Article
Dans :	International journal of epidemiology (vol. 34, n° 1, 2005)
Pagination :	215-220
Langues:	Anglais
Mots-clés :	Essai thérapeutique ; Epidémiologie ; Recherche
Résumé :	[BDSP. Notice produite par INIST-CNRS nRR0x6AN. Diffusion soumise à autorisation]. Background : Regression to the mean (RTM) is a statistical phenomenon that can make natural variation in repeated data look like real change. It happens when unusually large or small measurements tend to be followed by measurements that are closer to the mean. Methods : We give some examples of the phenomenon, and discuss methods to overcome it at the design and analysis stages of a study. Results : The effect of RTM in a sample becomes more noticeable with increasing measurement error and when follow-up measurements are only examined on a sub-sample selected using a baseline value. Conclusions : RTM is a ubiquitous phenomenon in repeated data and should always be considered as a possible cause of an observed change. Its effect can be alleviated through better study design and use of suitable statistical methods.

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