Titre :
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Baseline self-perceived risk of HIV infection independently predicts the rate of HIV seroconversion in a prospective cohort of injection drug users. Commentary : Nutritional epidemiology. (2005)
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Auteurs :
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Evan WOOD ;
Robert-S HOGG ;
Thomas KERR ;
Kathy LI ;
Cari-L MILLER ;
Julio-Sg MONTANER ;
Martin-T SCHECHTER ;
STRATHDEE (Steffanie-A) / disc. : USA. International Health and Cross-Cultural Medicine. Department of Family and Preventive Medicine. University of California San Diego School of Medicine. San Diego. CA. ;
University of British Columbia. Faculty of Medicine. Department of Medicine. Vancouver. BC. CAN
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Type de document :
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Article
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Dans :
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International journal of epidemiology (vol. 34, n° 1, 2005)
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Pagination :
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152-159
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Langues:
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Anglais
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Mots-clés :
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Sida
;
Virose
;
Infection
;
Facteur risque
;
Epidémiologie
;
Toxicomanie
;
Voie intraveineuse
;
Etude prospective
;
Canada
;
Amérique
;
Toxicomane
;
Homme
;
Immunopathologie
;
Amérique du Nord
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Résumé :
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[BDSP. Notice produite par INIST-CNRS I4R0xE6P. Diffusion soumise à autorisation]. Background : The identification of individuals at the highest risk of human immunodeficiency virus (HIV) infection is critical for targeting prevention strategies. We evaluated self-perceived risk of HIV infection and rates of subsequent HIV seroconversion among a prospective cohort study of injection drug users (IDUs). Methods : We performed an analysis of the time to HIV infection among 994 baseline HIV negative IDUs enrolled in the Vancouver injection drug users study (VIDUS). IDUs were stratified based on their baseline self-perceived risk of HIV seroconversion (higher than others vs same or lower). Kaplan-Meier methods were used to estimate cumulative HIV incidence rates and Cox regression was used to determine adjusted relative hazards for HIV seroconversion. Results : At the end of 24 months after enrolment into the cohort, the cumulative HIV incidence rate was significantly elevated among the 5.9% of the sample who perceived their risk for HIV infection to be higher at baseline (26.6% vs 7.8% log-rank P
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