| Titre : | Assessment of publication bias in meta-analyses of cardiovascular diseases. (2005) |
| Auteurs : | Silvia PALMA ; Miguel DELGADO-RODRIGUEZ ; University of Jaen. Division of Preventive Medicine and Public Health. ESP |
| Type de document : | Article |
| Dans : | Journal of epidemiology and community health (vol. 59, n° 10, 2005) |
| Pagination : | 864-869 |
| Langues: | Anglais |
| Mots-clés : | Biais ; Appareil circulatoire [pathologie] ; Evaluation ; Qualité |
| Résumé : | [BDSP. Notice produite par INIST-CNRS FNaDR0xT. Diffusion soumise à autorisation]. Objective : To examine variables related with publication bias assessment in a sample of systematic reviews with meta-analysis on cardiovascular diseases. Design : Systematic review of meta-analyses. Setting : Journals indexed in Medline and the Cochrane Library. Study population : 225 reviews with meta-analysis published between 1990 and 2002. Data collection : Data from meta-analyses were gathered according to a structured protocol. The outcome was the assessment, not the existence, of publication bias by the original authors. Results : Publication bias was assessed in 25 (11.1%) reviews, increasing with time : from 3.4% before 1998 to 19.0% in those published in 2002. A stepwise logistic regression model included several variables increasing the assessment of publication bias : number of primary studies (>7 compared with<=7, odds ratio (OR)=5.40,95% Cl=1.36 to 21.44), number of searched databases (>=4 compared with<3, OR=8.58,95% Cl=1.73 to 42.62), to be a meta-analysis on observational studies (OR=3.60,95% Cl=1.04 to 12.49), and year of publication (2002 compared with<2000, OR=5.73,95% Cl=1.16 to 28.36). In reviews published in the Cochrane Library publication bias was less frequently assessed (OR=0.06,95% Cl=0.01 to 0.69). Conclusions : The frequency of assessment of publication bias in meta-analysis is still very low, although it has improved with time. It is more frequent in meta-analyses on observational studies and it is related to other methodological characteristics of reviews. |
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