| Titre : | Intensity of smoking and smoking cessation in relation to risk of cataract extraction : A prospective study of women. (2005) |
| Auteurs : | LINDBLAD (Birgitta-Ejdervik) : SWE. Department of Ophthalmology. Sundsvall Hospital. Sundsvall. ; Niclas HAKANSSON ; PHILIPSON (B.O.) : SWE. Stockholm Eye Clinic. H M Queen Sophia Hospital. Stockholm. ; SVENSSON (Hanna) : SWE. Department of Medical Epidemiology and Biostatistics. Karolinska Institutet. Stockholm. ; Alicja WOLK |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 162, n° 1, 2005) |
| Pagination : | 73-79 |
| Langues: | Anglais |
| Mots-clés : | Tabagisme ; Arrêt ; Cataracte ; Tabac ; Sevrage ; Désaccoutumance ; Etude prospective ; Femme ; Homme ; Epidémiologie ; Oeil [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS wZL5R0xT. Diffusion soumise à autorisation]. The authors investigated the association of smoking and smoking cessation with the incidence of cataract extraction in a population-based prospective cohort study. A total of 34,595 women aged 49-83 years in the Swedish Mammography Cohort were followed from September 1997 through June 2002. Information on smoking, diet, and other lifestyle factors was collected through a self-administered questionnaire. A total of 2,128 cases of age-related cataract extraction were identified. Relative risks were estimated as rate ratios using Cox proportional hazards models. The authors observed a significant dose-response association between intensity of smoking and risk of cataract extraction (among current smokers, p for trend=0.02 ; among past smokers, p for trend=0.0002). After cessation of smoking, the risk decreased with time. Among women with a moderate lifetime smoking intensity (6-10 cigarettes/day), the relative risk was not significantly different from the risk among never smokers 10 years after smoking cessation. Among women who had smoked more intensively (>10 cigarettes/day), after 20 years of nonsmoking the increased risk became small and no longer statistically significant in comparison with never smokers (for trend over time, p<0.0001). This prospective study confirmed smoking as a risk factor for cataract, with a dose response for smoking intensity. Smoking cessation predicts reduced risk over time, but a longer period of time is needed with a higher smoking intensity. |
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