| Titre : | Assessing case definitions in the absence of a diagnostic gold standard. (2005) |
| Auteurs : | David COGGON ; EVANOFF (Bradley) : USA. Division of General Medical Sciences. Department of Medicine. Washington University School of Medicine. St Louis. MO. ; Christopher MARTYN ; Keith-T PALMER ; University of Southampton. Southampton General Hospital. Mrc Environmental Epidemiology Unit. Southampton. GBR |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 34, n° 4, 2005) |
| Pagination : | 949-952 |
| Langues: | Anglais |
| Mots-clés : | Définition ; Diagnostic ; Epidémiologie ; Norme ; Classification ; Validité ; Homme |
| Résumé : | [BDSP. Notice produite par INIST-CNRS VH2iR0xr. Diffusion soumise à autorisation]. Optimal case definition is important in epidemiological research, but can be problematic when no satisfactory gold standard is available. In particular, difficulties arise where the pathology underlying a disorder is unknown or cannot be reliably diagnosed. This problem can be overcome if diagnoses are viewed not necessarily as labels for disease processes, but more generally as a useful method for classifying people for the purpose of preventing or managing illness. With this perspective, the value of a case definition lies in its practical utility in distinguishing groups of people whose illnesses share the same causes or determinants of outcome (including response to treatment). A corollary is that the best-case definition for a disorder may vary according to the purpose for which it is being applied. |
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