| Titre : | Increased resting heart rate with pollutants in a population based study. (2005) |
| Auteurs : | Jean-Bernard RUIDAVETS ; Vincent Bataille ; CASSADOU (Sylvie) : FRA. InVs. Toulouse. ; Maxime COURNOT ; Jean FERRIERES ; MEYBECK (Mariam) : FRA. Oramip. Toulouse. ; University School of Medicine. Department of Epidemiology. Inserm U558. Toulouse. FRA |
| Type de document : | Article |
| Dans : | Journal of epidemiology and community health (vol. 59, n° 8, 2005) |
| Pagination : | 685-693 |
| Langues: | Anglais |
| Mots-clés : | Polluant ; Santé environnementale ; Médecine environnementale ; Appareil circulatoire [pathologie] ; Homme ; Pollution atmosphérique ; France ; Europe ; Fréquence cardiaque |
| Résumé : | [BDSP. Notice produite par INIST-CNRS R0xXC1qD. Diffusion soumise à autorisation]. Background : Air pollution is associated with cardiovascular mortality. Changes in the autonomic nervous system may contribute to cardiac arrhythmias and cardiovascular mortality. This study investigated the relations between air pollutant concentrations of sulphur dioxide (SO2), ozone (O3), nitric dioxide (NO2), and resting heart rate (RHR) in a population based study. Methods : A sample of 863 middle aged men and women, living in Toulouse (MONICA centre) area, was randomly recruited. A cross sectional survey on cardiovascular risk factors was carried. RHR was measured twice in a sitting position after a five minute rest. Multivariate analyses with quintiles of RHR were performed using polytomous logistic regression. Models were adjusted for temperature, season, relative humidity, sex, physical activity, blood pressure, C reactive protein, and cardiovascular drugs. Results : For NO2, the OR (odds ratio) (95% Cl) associated with an increase of 5 mug/m3in the current day of medical examination was 1.14 (1.03 to 1.25) in quintile Q5 of RHR compared with Q1, p for trend=0.003. For SO2, OR was 1.16 (0.94 to 1.44) in Q5 compared with Q1, p for trend=0.05, and for O3, OR was 0.96 (0.91 to 1.01) in Q5 compared with Q1, p for trend=0.11. No significant association was seen when the daily mean concentration of NO2, SO2, and O3 was considered during the previous day as well as when day lag 2 or 3 was considered. The cumulative concentration (three consecutive days) of O3 is negatively associated with RHR (p for trend=0.02). Conclusion : Changes in pulse rate could reflect cardiac rhythm changes and may be part of the pathophysiological link between pollution and cardiovascular mortality. |
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