| Titre : | The study of infectious intestinal disease in England : what risk factors for presentation to general practice tell us about potential for selection bias in case-control studies of reported cases of diarrhoea. (2003) |
| Auteurs : | Clarence-C TAM ; Sarah-J O'BRIEN ; Laura-C RODRIGUES ; Gastrointestinal Diseases Division. Communicable Disease Surveillance Centre. London. GBR ; Infectious Disease Epidemiology Unit. Department of Infectious & Tropical Diseases. London School of Hygiene & Tropical Medicine. Keppel Street. London. GBR |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 32, n° 1, 2003) |
| Pagination : | 99-105 |
| Langues: | Anglais |
| Mots-clés : | Diarrhée ; Infection ; Angleterre ; Grande Bretagne ; Royaume Uni ; Europe ; Facteur risque ; Surveillance épidémiologique ; Epidémiologie ; Biais ; Enquête cas témoin ; Médecine générale ; Homme ; Appareil digestif [pathologie] ; Intestin [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS LEsxR0xv. Diffusion soumise à autorisation]. Background Cases reported to national surveillance systems commonly form the sampling frame for population-based case-control studies of infectious intestinal diseases (IID). However, reported cases represent a minority of all cases in the population, differ systematically from unreported cases, and their use in case-control studies could introduce biases. Case reporting is a selective process involving multiple stages, the first of which requires presentation by a symptomatic person to the health services. Factors affecting a person's likelihood of presentation will thus affect the characteristics of reported cases. Methods Data from a large study of IID in England were used to investigate factors influencing presentation to a general practitioner (GP) following an episode of IID. Multivariable logistic regression was performed, comparing GP presenters with non-presenters. Explanatory variables used were illness severity, recent foreign travel and socioeconomic indicators. Results Severe illness (OR=12. 54,95% CI : 7.58-20.74), recent foreign travel (OR=2.4,95% CI : 1.39-4.14), leaving full-time education at an earlier age (OR=2.06,95% CI : 1.22-3.50) and housing categories representing lower socioeconomic status (SES) were all independently associated with GP presentation. Conclusions Case reporting to national surveillance is shaped by complex biological and social factors, of which illness severity appears to be the most important. Results from case-control studies comparing cases of IID identified by surveillance with population controls are likely to generalize mainly to cases severe enough to be reported. Controlling for educational and SES (mostly housing) is required. |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact