| Titre : | IARC monographs on the evaluation of carcinogenic risks to humans. Volume 90. Human Papillomaviruses. : Monographies du CIRC sur l'évaluation des risques de cancérogénicité pour l'homme. |
| Auteurs : | International Agency for Research on Cancer (IARC) (Lyon, INT) ; World Health Organization (WHO) (Geneva, CHE) |
| Type de document : | Ouvrage |
| Editeur : | Lyon : International Agency for Research on Cancer, 2007 |
| Collection : | IARC monographs on the evaluation of carcinogenic risks to humans , num. 90 |
| ISBN : | 978-92-832-1290-4 |
| Description : | 670p. / tabl. |
| Langues: | Anglais |
| Classement : | FR82/ (CANCER) |
| Mots-clés : | Papillomavirus ; Toxicologie ; Carcinogène ; Mesure risque ; Cancer ; Facteur risque ; Exposition ; Produit chimique ; Toxique ; Santé environnementale ; Cancérologie ; Expérimentation animale ; Virus ; Maladie sexuellement transmissible |
| Résumé : | HPVs represent the most common infectious agents that are transmitted sexually throughout the world; the major risk factors are behaviours associated with sexual activity. Although most infections are asymptomatic and are cleared within a period of 2 years, genital HPV infection can lead to clinical disease, including anogenital warts, cervical neoplasia, cervical cancer and other anogenital cancers. The risk for persistence of infection and progression of the more than 40 genital HPV types to grade 3 cervical intraepithelial neoplasia (CIN3) and cancer differs widely. Persistent infection with carcinogenic HPVs occurs in virtually all cases of cervical cancer. Previous evaluations of HPVs have classified types 16 and 18 as carcinogenic to humans (Group 1), types 31 and 33 as probably carcinogenic to humans (Group 2A) and some types other than 16, 18, 31 and 33 as possibly carcinogenic to humans (Group 2B). At that time, the evaluation of types 16 and 18 was based on the strong association between infection with these HPVs and cervical cancer. For types 31 and 33, the association was less strong. The new epidemiological data reviewed in the present volume strongly support and further confirm the previous evaluation of types 16 and 18, and provide new evidence for other HPVs. |
| En ligne : | https://monographs.iarc.who.int/monographs-available/ |
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