| Titre : | Absolute temperature, temperature changes and stroke risk : A case-crossover study. (2005) |
| Auteurs : | C. KYOBUTUNGI ; H. BECHER ; GRAU (A.) : DEU. Department of Neurology. University of Heidelberg. Heidelberg. ; G. STIEGLBAUER |
| Type de document : | Article |
| Dans : | European journal of epidemiology (vol. 20, n° 8, 2005) |
| Pagination : | 693-698 |
| Langues: | Anglais |
| Mots-clés : | Accident cérébrovasculaire ; Température ; Changement ; Facteur risque ; Risque ; Enquête cas témoin ; Climat ; Epidémiologie ; Appareil circulatoire [pathologie] ; Vaisseau sanguin encéphale [pathologie] ; Système nerveux [pathologie] ; Vaisseau sanguin [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS ARuR0x5u. Diffusion soumise à autorisation]. Studies suggest that there is an association between weather patterns and ischemic stroke risk. Exposure to a sudden decrease in temperature may increase stroke risk through altering blood viscosity and/or by triggering infections. We investigated the association between ischemic stroke risk and change in temperature. We used a case-crossover study design with 303 consecutive patients admitted to Heidelberg University, Department of Neurology over a one and a half year period (Aug 1998-Jan 2000). We used one day before stroke as the hazard (case) period matched to two control periods 2-7 days before and after stroke onset and took both ambient maximum temperature and the 24-hour difference in maximum temperature as exposure. There was no risk associated with ambient maximum temperature at all lag times and in all subgroup analyses. For the 24-hour difference, large changes in temperature (>5 °C) were associated with an increased risk of acute ischemic stroke regardless of whether the change was negative or positive. The odds ratio for temperature increases>5 °C compared to no change in temperature was 2.0 (95% confidence interval (CI) : 0.7-5.9) at a lag time of 3 days. We found no relevant relation between temperature and stroke risk. The results suggest that the risk of ischemic stroke may increase with large day-to-day variations upwards or downwards in temperature. |
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