| Titre : | Incidence of HIV-1 infection in adults and socio-demographic characteristics of seroconverters in a rural population in Uganda : 1990-1994. (1996) |
| Auteurs : | J.F. KENGEYA-KAYONDO ; A. KAMALI ; D.W. MULDER ; A.J. NUNN ; A. RUBERANTWARI ; H-Uh WAGNER ; Medical Research Council Uk Programme on Aids in Uganda. UGA ; Uganda Virus Research Institute. Po Box 49. Entebbe. UGA |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 25, n° 5, 1996) |
| Pagination : | 1077-1082 |
| Langues: | Anglais |
| Mots-clés : | Virose ; Infection ; Virus ; Epidémiologie ; Incidence ; Milieu rural ; Adulte ; Homme ; Ouganda ; Afrique ; Facteur risque ; Démographie ; Facteur socioéconomique ; Age ; Sexe ; Maladie autoimmune ; Sida |
| Résumé : | [BDSP. Notice produite par INIST oITR0xZw. Diffusion soumise à autorisation]. Background. To evaluate HIV-1 incidence among adults and socio-demographic risk factors in a rural population in Uganda, a prospective cohort study was carried out. Methods. All consenting adult residents in a cluster of 15 neighbouring villages of the Masaka District of south-west Uganda have been participating in annual socio-demographic and serological surveys since November 1989. Those who had a negative serostatus when they were first tested and had at least one serostatus assessment during the 4 years of follow-up (1990-1994) have been evaluated for HIV-1 seroconversion. Incidence rates have been calculated per 1000 person-years of observation and socio-demographic characteristics assessed for association with recent seroconversion. Results. At the baseline survey, of 4175 adults with assessable serostatus (79% of all censused adults), 342 (8.2%) were seropositive. During 12 588.2 person-years of follow-up 89 seroconversions were identified corresponding to an incidence rate of 7.1 (95% CI : 5.6-8.5). Overall rates were highest in females aged 20-24 years (15.2) and in males aged 20-44 years (11.6). There was a significant interaction between age and sex ; the ratio of the rate in females to that in males decreased from 3.3 : 1 to 0.5 : 1 with increasing age. Rates for males aged 20 years were four times higher than those for younger males. (...) |

