Titre :
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Incidence of HIV-1 infection in adults and socio-demographic characteristics of seroconverters in a rural population in Uganda : 1990-1994. (1996)
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Auteurs :
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J.F. KENGEYA-KAYONDO ;
A. KAMALI ;
D.W. MULDER ;
A.J. NUNN ;
A. RUBERANTWARI ;
H-Uh WAGNER ;
Medical Research Council Uk Programme on Aids in Uganda. UGA ;
Uganda Virus Research Institute. Po Box 49. Entebbe. UGA
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Type de document :
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Article
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Dans :
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International journal of epidemiology (vol. 25, n° 5, 1996)
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Pagination :
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1077-1082
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Langues:
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Anglais
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Mots-clés :
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Virose
;
Infection
;
Virus
;
Epidémiologie
;
Incidence
;
Milieu rural
;
Adulte
;
Homme
;
Ouganda
;
Afrique
;
Facteur risque
;
Démographie
;
Facteur socioéconomique
;
Age
;
Sexe
;
Maladie autoimmune
;
Sida
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Résumé :
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[BDSP. Notice produite par INIST oITR0xZw. Diffusion soumise à autorisation]. Background. To evaluate HIV-1 incidence among adults and socio-demographic risk factors in a rural population in Uganda, a prospective cohort study was carried out. Methods. All consenting adult residents in a cluster of 15 neighbouring villages of the Masaka District of south-west Uganda have been participating in annual socio-demographic and serological surveys since November 1989. Those who had a negative serostatus when they were first tested and had at least one serostatus assessment during the 4 years of follow-up (1990-1994) have been evaluated for HIV-1 seroconversion. Incidence rates have been calculated per 1000 person-years of observation and socio-demographic characteristics assessed for association with recent seroconversion. Results. At the baseline survey, of 4175 adults with assessable serostatus (79% of all censused adults), 342 (8.2%) were seropositive. During 12 588.2 person-years of follow-up 89 seroconversions were identified corresponding to an incidence rate of 7.1 (95% CI : 5.6-8.5). Overall rates were highest in females aged 20-24 years (15.2) and in males aged 20-44 years (11.6). There was a significant interaction between age and sex ; the ratio of the rate in females to that in males decreased from 3.3 : 1 to 0.5 : 1 with increasing age. Rates for males aged 20 years were four times higher than those for younger males. (...)
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