| Titre : | Associations between body height, body composition and cholesterol levels in middle-aged men. The coronary risk factor study in southern Sweden (CRISS). (2001) |
| Auteurs : | Karin-M HENRIKSSON ; B. AGREN ; U. LINDBLAD ; P. NILSSON-EHLE ; L. RASTAM |
| Type de document : | Article |
| Dans : | European journal of epidemiology (vol. 17, n° 6, 2001) |
| Pagination : | 521-526 |
| Langues: | Anglais |
| Mots-clés : | Cardiopathie coronaire ; Taille corporelle ; Poids corporel ; Epidémiologie ; Facteur risque ; Homme ; Suède ; Europe ; Appareil circulatoire [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS R0x9IT8J. Diffusion soumise à autorisation]. Background : Short body height is associated with increased risk for coronary heart disease ; however, mechanisms are not fully explained. In this study, associations between body height and serum cholesterol, non-high-density lipoprotein (non-HDL cholesterol) and high-density lipoprotein (HDL cholesterol) were investigated. Methods : Prospective cohort study of middle-aged men from Helsingborg, Sweden starting 1990. Two birth-year cohorts were invited at 37,40 and 43 years of age ; participation at baseline was 991 (68%). Serum and HDL cholesterol, systolic and diastolic blood pressure, weight, height, waist and hip circumferences were measured. Non-HDL cholesterol, body mass index (BMI) and waist/hip ratio (WHR) were calculated. The participants completed a questionnaire covering lifestyle variables. Results : There were statistically significant inverse correlations between body height and serum cholesterol (-0.11) and non-HDL cholesterol (-0.12). One standard deviation, 6.7 cm, taller body height was associated with a lower serum cholesterol (-0.12 mmol/l) and a lower non-HDL cholesterol (-0.13 mmol/l ; p<0.001). These associations remained when adjusted for BMI and WHR. Men with serum cholesterol equal to or above 6.5 mmol/l were significantly shorter (mean 178.71 cm) than men with serum cholesterol below 6.5 mmol/l (mean 179.71 cm). In addition, BMI and WHR were positively associated with serum and non-HDL cholesterol and inversely associated with HDL cholesterol. The change in cholesterol levels over the six-year follow-up was significantly associated to the change in BMI and WHR. Conclusions : Body height had an independent and inverse relation to serum cholesterol and non-HDL cholesterol in middle-aged men, and the lipid pattern suggests that the underlying mechanism might be different from the traditional association between lipids and the metabolic syndrome. (...) |
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