| Titre : | Preterm birth, vascular function, and risk factors for atherosclerosis. (2001) |
| Auteurs : | Atul SINGHAL ; Tim-J COLE ; John DEANFIELD ; M.I.A. KATTENHORN ; Alan Lucas ; Department of Vascular Physiology. Institute of Child Health. Guilford Street. London. GBR ; Mrc Childhood Nutrition Research Centre. Institute of Child Health. Guilford Street. London. GBR |
| Type de document : | Article |
| Dans : | Lancet (The) (vol. 358, n° 9288, 2001) |
| Pagination : | 1159-1160 |
| Langues: | Anglais |
| Mots-clés : | Prématurité ; Artériosclérose ; Facteur risque ; Etude comparée ; Epidémiologie ; Royaume Uni ; Europe ; Nouveau né ; Homme ; Adolescent ; Appareil circulatoire [pathologie] ; Vaisseau sanguin [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS R0xt7RKh. Diffusion soumise à autorisation]. Low birthweight may predispose to the development of atherosclerosis later in life. We have tested the hypothesis that low birthweight as a result of preterm birth Is associated with reduced flow-mediated endothellal-dependent vasodilation (FMD), which is an early stage in the development of atherosclerosis. Mean FMD in adolescents born preterm who had a low birthwelght did not differ from that for controls born at term (0.225 mm vs 0.220 mm, SD 0.1 for both means, p=0.78). Our findings indicate that low birthwelght attributable to prematurity does not increase the risk of vascular disease later In life. |

