| Titre : | Effect of release from prison and re-incarceration on the viral loads of HIV-infected individuals. (2005) |
| Auteurs : | Becky-L STEPHENSON ; GOLIN (Carol-E) : USA. Department of Health Behavior and Health Education. School of Public Health. University of North Carolina at Chapel Hill. Chapel Hill. NC. ; Andrew-H KAPLAN ; Paul STEWART ; Hsiao-Chuan TIEN ; David-A WOHL ; University of North Carolina at Chapel Hill. School of Public Health. Department of Biostatistics. Chapel Hill. NC. USA ; University of North Carolina School of Medicine. Department of Medicine. Division of Infectious Diseases. Chapel Hill. NC. USA |
| Type de document : | Article |
| Dans : | Public health reports (vol. 120, n° 1, Janvier/Février 2005) |
| Pagination : | 84-88 |
| Langues: | Anglais |
| Mots-clés : | Sida ; Virose ; Infection ; Prison ; Homme ; Etats Unis ; Amérique ; Immunopathologie ; Amérique du Nord |
| Résumé : | [BDSP. Notice produite par INIST-CNRS o2R0xPR9. Diffusion soumise à autorisation]. Objectives. The purpose of this study was to determine the effect of release from prison and subsequent re-incarceration on the viral loads of HIV-infected individuals receiving highly active antiretroviral therapy (HAART). Methods. Fifteen re-incarcerated HIV-infected prisoners on HAART were identified from a retrospective cohort of HIV-infected prison inmates released from January 1,1997, to August 31,1999. The re-incarcerated prisoners were matched (1 : 2) to 30 HIV-infected incarcerated prisoners on HAART who remained incarcerated during the re-incarcerated participants'release time period. The outcomes measured were plasma HIV RNA levels, CD4+lymphocyte counts, percentage of re-incarcerated and incarcerated participants with plasma HIV RNA levels<400 copies/mL, and the median change in plasma HIV RNA levels of the re-incarcerated and incarcerated participants at the end of the study. Results. At the beginning of the study, 8/15 re-incarcerated participants had plasma HIV RNA levels<400 copies/mL, compared with 15/30 incarcerated participants. At the end of the study, only three of those eight re-incarcerated participants had plasma HIV RNA levels<400 copies/mL, compared with 14/15 incarcerated participants (p=0.0086). The median change in plasma HIV RNA levels of the re-incarcerated participants was 1.29 log10 copies/mL (interquartile range 0.04 to 1.70), compared with - 0.03 log10 copies/mL (interquartile range - 0.65 to 0.09) in the incarcerated participants (p=0.0183). Conclusions. Release from prison was associated with a deleterious effect on virological and immunological outcomes. These data suggest that comprehensive discharge planning efforts are required to make certain that HIV-infected inmates receive access to quality care following incarceration. |
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