| Titre : | Alcohol consumption and the risk of type 2 diabetes mellitus : Atherosclerosis Risk in Communities Study. (2001) |
| Auteurs : | Whlinda KAO ; Lori-L BOLAND ; Frederick-L BRANCATI ; Ian-B PUDDEY ; Robert-L WATSON ; Department of Epidemiology. Bloomberg School of Public Health. Johns Hopkins University. Baltimore. MD. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 154, n° 8, 2001) |
| Pagination : | 748-757 |
| Langues: | Anglais |
| Mots-clés : | Diabète non insulinodépendant ; Alcool ; Consommation alimentaire ; Facteur risque ; Epidémiologie ; Homme ; Femme ; Glande endocrine [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS s7N6R0x3. Diffusion soumise à autorisation]. Evidence regarding the association between alcohol consumption and type 2 diabetes risk remains inconsistent, particularly with regard to male-female differences. The authors conducted a prospective study of type 2 diabetes risk associated with alcohol consumption in a cohort of 12,261 middle-aged participants of the Atherosclerosis Risk in Communities Study (1990-1998), who were followed between 3 and 6 years. Alcohol consumption at baseline was characterized into lifetime abstainers, former drinkers, and current drinkers of various levels. Incident diabetes was determined by blood glucose measurements and self-report. After adjustment for potential confounders, an increased risk of diabetes was found in men who drank>21 drinks/week when compared with men who drank<1 drink/week (odds ratio=1.50,95% confidence interval : 1.02,2.20) while no significant association was found in women. This increased diabetes risk among men who drank>21 drinks/week was predominantly related to spirits rather than to beer or wine consumption. The relative odds of incident diabetes in a comparison of men who drank>14 drinks of spirits per week with men who were current drinkers but reported no regular use of spirits, beer, or wine were 1.82 (95% confidence interval : 1.14,2.92). Results of this study support the hypothesis that high alcohol intake increases diabetes risk among middle-aged men. However, more moderate levels of alcohol consumption do not increase risk of type 2 diabetes in either middle-aged men or women. Am J Epidemiol 2001 ; 154 : 748-57. |
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