Titre :
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Use of topical sunscreens and the risk of malignant melanoma : A meta-analysis of 9067 patients from 11 case-control studies. (2002)
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Auteurs :
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HUNCHAREK (Michael) : USA. Division of Radiation Oncology. Department of Clinical Oncology Marshfield Clinic Cancer Center. Marshfield. WI. ;
KUPELNICK (Bruce) : USA. Meta-Analysis Research Group. Stevens Point.
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Type de document :
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Article
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Dans :
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American journal of public health (vol. 92, n° 7, 2002)
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Pagination :
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1173-1177
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Langues:
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Anglais
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Mots-clés :
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Peau
;
Homme
;
Epidémiologie
;
Facteur risque
;
Soleil
;
Cancer
;
Peau [pathologie]
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Résumé :
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[BDSP. Notice produite par INIST-CNRS hR0xT60c. Diffusion soumise à autorisation]. Objectives. This study examined the methodolgoy of epidemiological studies that suggest use of topical sunscreen preparations is associated with increased risk of malignant melanoma. Methods. We pooled data from observational studies using a general variance-based meta-analytic method that employed confiderice intervals (previously described). The outcome of interest was a summary relative risk (RR) reflecting the tisk of melanoma as sociated with sunscreen use versus nonuse. Sensitivity analyses were performed when necessary to explain any observed statistical heterogeneity. Results. Combining studies that used nonheterogeneous data yielded a summary RR of 1.01, indicating no association between sunscreen use and development of malignant melanoma. Conclusions. The available epidemiological data do not support the existence of a relationship between topical sunscreen use and an increased risk of cutaneous malignant melanoma.
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