| Titre : | Night blindness of pregnancy in rural Nepal : nutritional and health risks. (1998) |
| Auteurs : | P. CHRISTIAN ; J. KATZ ; S.K. KHATRY ; S.C. LECLERQ ; R.P. POKHREL ; E.K. PRADHAN ; SHARDA RAM SHRESTHA . (.) ; Kpjr WEST ; Center for Human Nutrition. And the Department of International Health. School of Hygiene and Public Health. Johns Hopkins University. Baltimore MD. USA ; National Society for the Prevention of Blindness Nepal Netra Jyoti Sangh Kathmandu. NPL |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 27, n° 2, 1998) |
| Pagination : | 231-237 |
| Langues: | Anglais |
| Mots-clés : | Grossesse ; Déficit ; Vitamine A ; Ration alimentaire ; Epidémiologie ; Facteur risque ; Homme ; Femme ; Népal ; Asie ; Oeil [pathologie] ; Trouble vision ; Alimentation |
| Résumé : | [BDSP. Notice produite par INIST 9R0xKeMr. Diffusion soumise à autorisation]. Background Night blindness (XN) is the most common clinical symptom of vitamin A deficiency among children in developing countries. Yet little is known about the aetiology or associated risks of maternal XN. Emerging evidence from South East Asia suggests that it may be more frequent than previously thought in women of reproductive age, especially during pregnancy. Methods A population-based, case-control study was conducted to reveal the epidemiology of XN among pregnant Nepali women. Night blind cases were identified by history through a weekly community surveillance system. Controls were randomly selected from a pool of pregnant women without XN and pair-matched for gestational age of the cases. A home-based assessment was done within a week of selection, at which 7-day food frequency and morbidity histories were collected, anthropometry measured, and capillary blood drawn for serum retinol, 5-carotene and haemoglobin (Hb) estimation. Results Cases and controls did not differ by age or number of previous pregnancies. However, cases were more likely to be from the lower castes, be illiterate, live in poorer quality homes, and own no land. The mean serum retinol level of cases was ~0.30 mumol/l lower than controls (P<0.001), indicating a low vitamin A status of night blind pregnant women. Mean Hb level was significantly lower (by 0.7 g/dl, P<0.004), and the risk of severe anaemia (Hb<7.0 g/dl) higher among cases than controls (odds ratio=3.0,95% CI : 1.25-7.23). (...) |
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