| Titre : | Birth Defects among Infants Born to Women Who Received Anthrax Vaccine in Pregnancy. (2008) |
| Auteurs : | Margaret-Ak RYAN ; Jdavid ERICKSON ; William-K HONNER ; Rosha-A LOACH ; Cynthia-A MOORE ; Carter-J SEVICK ; Tyler-C Smith ; Us Department of Defense Center for Deployment Health Research. Naval Health Research Center. San Diego. CA. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 168, n° 4, 2008) |
| Pagination : | 434-442 |
| Langues: | Anglais |
| Mots-clés : | Malformation ; Nouveau né ; Nourrisson ; Femme enceinte ; Femme ; Vaccination ; Vaccin ; Grossesse ; Prévention santé ; Maladie congénitale ; Homme ; Bactériose ; Infection |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 7Hl8R0xl. Diffusion soumise à autorisation]. In response to bioterrorism threats, anthrax vaccine has been used by the US military and considered for civilian use. Concerns exist about the potential for adverse reproductive health effects among vaccine recipients. This retrospective cohort evaluated birth defects, in relation to maternal anthrax vaccination, among all infants born to US military service women between 1998 and 2004. Department of Defense databases defined maternal vaccination and infant diagnoses ; multivariable regression models described potential associations between anthrax vaccination and birth defects in liveborn infants. Among 115,169 infants born to military women during this period, 37,140 were born to women ever vaccinated against anthrax, and 3,465 were born to women vaccinated in the first trimester of pregnancy. Birth defects were slightly more common in first trimester-exposed infants (odds ratio=1.18,95% confidence interval : 0.997,1.41) when compared with infants of women vaccinated outside of the first trimester, but this association was statistically significant only when alternative referent groups were used. Although the small observed association may be unlikely to represent a causal relation between vaccination in early pregnancy and birth defects, this information should be considered when making decisions about administering anthrax vaccine to pregnant women. |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact