| Titre : | Prospective Study of Alcohol Consumption Quantity and Frequency and Cancer-Specific Mortality in the US Population. (2011) |
| Auteurs : | BRESLOW (Rosalind-A) : USA. National Institute on Alcohol Abuse and Alcoholism. Bethesda. MD. ; CHEN (Chiung-M) : USA. Csr Inc. Arlington. VA. ; GRAUBARD (Barry-I) : USA. Biostatistics Branch. Division of Cancer Epidemiology and Genetics. National Cancer Institute. Bethesda. MD. ; MUKAMAL (Kenneth-J) : USA. Division of General Medicine and Primary Care. Beth Israel Deaconess Medical Center. Boston. MA. |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 174, n° 9, 2011) |
| Pagination : | 1044-1053 |
| Langues: | Anglais |
| Mots-clés : | Cancer ; Etude prospective ; Boisson alcoolisée ; Consommation ; Fréquence ; Epidémiologie ; Mortalité ; Régime alimentaire ; Habitude alimentaire ; Facteur risque ; Amérique ; Amérique du Nord |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 8R0xoAH9. Diffusion soumise à autorisation]. Prospective associations between quantity and frequency of alcohol consumption and cancer-specific mortality were studied using a nationally representative sample with pooled data from the 1988,1990,1991, and 1997-2004 administrations of the National Health Interview Survey (n=323,354). By 2006,8,362 participants had died of cancer. Cox proportional hazards regression was used to estimate relative risks. Among current alcohol drinkers, for all-site cancer mortality, higher-quantity drinking (>3 drinks on drinking days vs. 1 drink on drinking days) was associated with increased risk among men (relative risk (RR)=1.24,95% confidence interval (CI) : 1.09,1.41 ; Pfor linear trend=0.001) ; higher-frequency drinking (>3 days/week vs.<1 day/week) was associated with increased risk among women (RR=1.32,95% CI : 1.13,1.55 ; P-trend<0.001). Lung cancer mortality results were similar, but among never smokers, results were null. For colorectal cancer mortality, higher-quantity drinking was associated with increased risk among women (RR=1.93,95% CI : 1.17,3.18 ; P-trend=0.03). Higher-frequency drinking was associated with increased risk of prostate cancer (RR=1.55,95% CI : 1.01,2.38 ; Pfor quadratic effect=0.03) and tended to be associated with increased risk of breast cancer (RR=1.44,95% CI : 0.96,2.17 ; P-trend=0.06). Epidemiologic studies of alcohol and cancer mortality should consider the independent effects of quantity and frequency. |
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