| Titre : | Impact of maternal asthma on perinatal outcomes : a two-stage sampling cohort study. (2012) |
| Auteurs : | Faranak FIROOZI ; Marie-France Beauchesne ; Lucie Blais ; Amélie FORGET ; Catherine LEMIERE ; Sylvie PERREAULT ; Faculty of Pharmacy. Universite de Montreal. Succursale Centre-ville. Montreal. QC. CAN ; Research Center. Hôpital du Sacré-Coeur de Montreal. Montreal. QC. CAN |
| Type de document : | Article |
| Dans : | European journal of epidemiology (vol. 27, n° 3, 2012) |
| Pagination : | 205-214 |
| Langues: | Anglais |
| Mots-clés : | Asthme ; Mère ; Hypotrophie foetale ; Nouveau né ; Pronostic ; Evolution ; Prélèvement ; Femme ; Femme enceinte ; Grossesse ; Prématurité ; Nourrisson ; Epidémiologie ; Homme ; Bronchopneumopathie obstructive |
| Résumé : | [BDSP. Notice produite par INIST-CNRS H8JnR0xE. Diffusion soumise à autorisation]. There are conflicting results concerning the impact of maternal asthma during pregnancy on perinatal outcomes. The present study investigated the associations between maternal asthma during pregnancy and the risk of a small-for-gestational-age (SGA) infant, a low-birth-weight (LBW) infant, and preterm birth. A population-based cohort of 40,788 pregnancies from asthmatic and non-asthmatic women was reconstructed through the linking of three Quebec (Canada) administrative databases between 1990 and 2002. A two-stage sampling cohort design was used to collect additional information by way of a mailed questionnaire. The generalized estimation equation models were used to obtain adjusted odds ratios of SGA, LBW and preterm birth comparing asthmatic and non-asthmatic women. The cohort included 13,007 pregnancies from asthmatic and 27,781 pregnancies from non-asthmatic women. Final estimates showed that the odds of SGA (odds ratio : 1.27,95% confidence interval : 1.14,1.41), LBW (1.41 : 1.22,1.63) and preterm delivery (1.64 : 1.46,1.83) were significantly higher among asthmatic than non-asthmatic women. Mothers with asthma during pregnancy are more likely to have SGA, LBW, or preterm birth infants than non-asthmatic women. These results can be more easily generalized to women with lower socio-economic status since the cohort under represents women with high socio-economic status. |
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