| Titre : | A Pooled Analysis of Extremely Low-Frequency Magnetic Fields and Childhood Brain Tumors. (2010) |
| Auteurs : | L. KHEIFETS ; A. AHLBOM ; C.M. CRESPI ; M. FEYCHTING ; C. JOHANSEN ; G. MEZEI ; J. MONROE ; M.F.G. MURPHY ; S. OKSUZYAN ; S. PRESTON-MARTIN ; E. ROMAN ; T. SAITO ; D. SAVITZ ; J. SCHUZ ; J. SIMPSON ; J. SWANSON ; T. TYNES ; P. VERKASALO |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 172, n° 7, 2010) |
| Pagination : | 752-761 |
| Langues: | Anglais |
| Mots-clés : | Enfant ; Encéphale ; Magnétisme ; Epidémiologie ; Homme ; Cerveau |
| Résumé : | [BDSP. Notice produite par INIST-CNRS pR0x9n9s. Diffusion soumise à autorisation]. Pooled analyses may provide etiologic insight about associations between exposure and disease. In contrast to childhood leukemia, no pooled analyses of childhood brain tumors and exposure to extremely low-frequency magnetic fields (ELF-MFs) have been conducted. The authors carried out a pooled analysis based on primary data (1960-2001) from 10 studies of ELF-MF exposure and childhood brain tumors to assess whether the combined results, adjusted for potential confounding, indicated an association. The odds ratios for childhood brain tumors in ELF-MF exposure categories of 0.1-<0.2 muT, 0.2-<0.4 muT, and>0.4 muT were 0.95 (95% confidence interval : 0.65,1.41), 0.70 (95% CI : 0.40,1.22), and 1.14 (95% CI : 0.61,2.13), respectively, in comparison with exposure of<0.1 muT. Other analyses employing alternate cutpoints, further adjustment for confounders, exclusion of particular studies, stratification by type of measurement or type of residence, and a nonparametric estimate of the exposure-response relation did not reveal consistent evidence of increased childhood brain tumor risk associated with ELF-MF exposure. These results provide little evidence for an association between ELF-MF exposure and childhood brain tumors. |
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