| Titre : | The association of the metabolic syndrome with QTc interval in NHANES III. (2008) |
| Auteurs : | Mohammed-F FARAMAWI ; Mohammed-Y ABDUL KAREEM ; Jeanette GUSTAT ; Janet RICE ; Rachel-P WILDMAN |
| Type de document : | Article |
| Dans : | European journal of epidemiology (vol. 23, n° 7, 2008) |
| Pagination : | 459-465 |
| Langues: | Anglais |
| Mots-clés : | Association ; Diabète ; Electrocardiographie ; Homme ; Epidémiologie ; Glande endocrine [pathologie] ; Electrodiagnostic |
| Résumé : | [BDSP. Notice produite par INIST-CNRS pIR0xsC8. Diffusion soumise à autorisation]. Purpose : To examine the relationship of metabolic syndrome with corrected QT interval duration. Methods : In a cross-sectional analysis of NHANES III, a representative sample of the adult US population, 3,495 individuals aged>=40 years were categorized as having metabolic syndrome and not having metabolic syndrome as defined by ATP III. QT interval was measured from the standard 12-lead electrocardiogram. Results : A weighted multi-linear regression analysis adjusted for age, gender, serum calcium, and potassium showed that metabolic syndrome was significantly associated with a corrected QT interval in milliseconds. The adjusted Beta coefficient and its corresponding standard error were (4.48 milliseconds, 0.95 milliseconds, P<0.01). Conclusion : These data indicate that metabolic syndrome is independently associated with a corrected QT interval duration. This study calls for careful ECG monitoring among persons with metabolic syndrome for early detection of a long corrected QT interval in order to prevent severe and often fatal arrhythmias. |
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