| Titre : | Leukaemia and occupation : a New Zealand Cancer Registry-based case-control Study. (2009) |
| Auteurs : | David MCLEAN ; Andrea 'T MANNETJE ; Aaron BLAIR ; Paolo BOFFETTA ; Soo CHENG ; Chris CUNNINGHAM ; Evan DRYSON ; Hans KROMHOUT ; Milena MAULE ; Fiona MCKENZIE ; Neil PEARCE ; Chris WALLS ; Centre for Public Health Research. Massey University. Wellington. NZL |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 38, n° 2, 2009) |
| Pagination : | 594-606 |
| Langues: | Anglais |
| Mots-clés : | Leucémie ; Métier ; Statut social ; Cancer ; Cancérologie ; Enquête cas témoin ; Epidémiologie ; Ouvrier agricole ; Agriculture ; Ouvrier ; Homme ; Océanie |
| Résumé : | [BDSP. Notice produite par INIST-CNRS IpG9sR0x. Diffusion soumise à autorisation]. Background : To examine the association between occupation and leukaemia. Methods : We interviewed 225 cases (aged 20-75 years) notified to the New Zealand Cancer Registry during 2003-04, and 471 controls randomly selected from the Electoral Roll collecting demographic details, information on potential confounders and a comprehensive employment history. Associations between occupation and leukaemia were analysed using logistic regression adjusted for gender, age, ethnicity and smoking. Results : Elevated odds ratios (ORs) were observed in agricultural sectors including horticulture/fruit growing (OR : 2.62,95% confidence interval (CI) : 1.51,4.55), plant nurseries (OR : 7.51,95% CI : 1.85,30.38) and vegetable growing (OR : 3.14,95% CI : 1.18,8.40) ; and appeared greater in women (ORs : 4.71,7.75 and 7.98, respectively). Elevated ORs were also observed in market farmers/crop growers (OR : 1.84,95% CI : 1.12,3.02), field crop/vegetable growers (OR : 3.98,95% CI : 1.46,10.85), market gardeners (OR : 5.50,95% CI : 1.59,19.02), and nursery growers/workers (OR : 4.23,95% CI : 1.34,13.35) ; also greater in women (ORs : 3.48,7.62,15.74 and 11.70, respectively). These elevated ORs were predominantly for chronic lymphocytic leukaemia (CLL). Several associations persisted after semi-Bayes adjustment. Elevated ORs were observed in rubber/plastics products machine operators (OR : 3.76,95% CI : 1.08,13.08), predominantly in plastic product manufacturing. CLL was also elevated in tailors and dress-makers (OR : 7.01,95% CI : 1.78,27.68), cleaners (OR : 2.04,95% CI : 1.00,4.14) and builder's labourers (OR : 4.03,95% CI : 1.30,12.53). Conclusions : These findings suggest increased leukaemia risks associated with certain agricultural, manufacturing, construction and service occupations in New Zealand. |
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