| Titre : | Statistical inference for the area under the receiver operating characteristic curve in the presence of random measurement error. (2001) |
| Auteurs : | Enrique-F SCHISTERMAN ; David FARAGGI ; Benjamin REISER ; Maurizio TREVISAN ; Department of Social and Preventive Medicine. University at Buffalo. Buffalo. NY. USA ; Department of Statistics. Haifa University. Haifa. ISR |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 154, n° 2, 2001) |
| Pagination : | 174-179 |
| Langues: | Anglais |
| Mots-clés : | Cardiopathie ; Homme ; Epidémiologie ; Méthodologie ; Fiabilité ; Appareil circulatoire [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 3HoDR0xZ. Diffusion soumise à autorisation]. The area under the receiver operating characteristic curve is the most commonly used measure of the ability of a biomarker to distinguish between two populations. Some markers are subject to substantial measurement error. Under normality assumptions, the authors develop a confidence interval procedure for the area under the receiver operating characteristic curve that adjusts for measurement error. This procedure assumes the availability of data from a reliability study of the biomarker. A simulation study was used to check the validity of the proposed confidence interval. Furthermore, it was shown that not adjusting for measurement error could result in a serious understatement of the effectiveness of the biomarker. |

