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Regional variation in incidence and case fatality of myocardial infarction among young women in England, Scotland and Wales.

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Titre :	Regional variation in incidence and case fatality of myocardial infarction among young women in England, Scotland and Wales. (2000)
Auteurs :	N.R. DUNN ; A. ARSCOTT ; L. DE CAESTECKER ; B. FARAGHER ; T.M. MACDONALD ; R.D. MANN ; C. MCCOLLUM ; S. Thomas ; M. THOROGOOD ; Drug Safety Research Unit. Bursledon Hall. Southampton. GBR
Type de document :	Article
Dans :	Journal of epidemiology and community health (vol. 54, n° 4, 2000)
Pagination :	293-298
Langues:	Anglais
Mots-clés :	Infarctus ; Myocarde ; Jeune adulte ; Homme ; Femme ; Evolution ; Epidémiologie ; Incidence ; Mortalité ; Royaume Uni ; Europe ; Appareil circulatoire [pathologie] ; Cardiopathie coronaire ; Myocarde [pathologie]
Résumé :	[BDSP. Notice produite par INIST 56R0xTy3. Diffusion soumise à autorisation]. Objectives-To examine the regional variation in incidence and case fatality of myocardial infarction among young women. Design-Cross sectional survey, using population based incidence data. Setting-England, Scotland and Wales. Subjects-Subjects were women aged 16-44 with a diagnosis of myocardial infarction between 1 October 1993 and 15 October 1995. Outcome measures-Incidence of myocardial infarction per 100 000 women years, with case fatality as a percentage of total cases. Results-Incidence of myocardial infarction rose steeply from age 33 upwards, (maximum=20.2 cases per 100 000 women years at age 44). The adjusted incidence rate for myocardial infarction was 3.7 (95% CI 3.2,4.2) times greater in Scotland than in southern England. In contrast, case fatality was significantly lower in Scotland : 18.5% (95% CI 13.1%, 25.0%), compared with 31.0% (95% CI 25.9%, 36.0%) in southern England. Conclusions-The incidence of myocardial infarction varied widely within the United Kingdom. Case fatality variation may reflect differences in ambulance response, or in diagnostic acumen, within the regions.