| Titre : | Directly observed highly active antiretroviral therapy for HIV-infected children in Cambodia. (2007) |
| Auteurs : | Patricia MYUNG ; Mark-F BRADY ; Joseph-I HARWELL ; Mark LURIE ; Phok MANY ; David PUGATCH ; John TUCKER ; Brown Medical School. Providence. RI. USA ; Maryknoll Little Sprouts program. Phnom Penh. KHM |
| Type de document : | Article |
| Dans : | American journal of public health (vol. 97, n° 6, 2007) |
| Pagination : | 974-977 |
| Langues: | Anglais |
| Mots-clés : | Sida ; Lutte contre sida ; Programme santé ; Médicament antiviral ; Enfant ; Cambodge ; Virose ; Infection ; Homme ; Asie ; Immunopathologie |
| Résumé : | [BDSP. Notice produite par INIST-CNRS aS8VR0x9. Diffusion soumise à autorisation]. Antiretroviral medications are becoming available for HIV-infected children in resource-limited settings. Maryknoll, an international Catholic charity, provided directly observed antiretroviral therapy to HIV-infected children in Phnom Penh, Cambodia. Child care workers administered generic antiretroviral drugs twice daily to children, ensuring adherence. Treatment began with 117 late-stage HIV-infected children ; 22 died of AIDS during the first 6 months. The rest were treated for at least 6 months and showed CD4 count increases comparable to those achieved in US and European children. Staffing cost for this program was approximately US$5 per child per month, or 15% more than the price of the medications. Drug toxicities were uncommon and easily managed. Directly observed antiretroviral therapy appears to be a promising, low-cost strategy for ensuring adherent treatment for HIV-infected children in a resource-limited setting. |
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