| Titre : | Short-Term Association Between Ambient Air Pollution and Risk of Hospitalization for Acute Myocardial Infarction : Results of the Cardiovascular Risk and Air Pollution in Tuscany (RISCAT) Study. (2011) |
| Auteurs : | NUVOLONE (Daniela) : ITA. Epidemiology Unit. Regional Agency for Public Health of Tuscany. Florence. ; Daniela BALZI ; Alessandro BARCHIELLI ; Marco CHINI ; Franco GIOVANNINI ; SCALA (Danila) : ITA. Epidemiology Unit. Regional Agency for Environmental Protection of Tuscany. Florence. ; Epidemiology Unit. Local Health Unit 10. Regional Health Service of Tuscany. Florence. ITA ; Regional Center for Protection of Air Quality. Regional Agency for Environmental Protection of Tuscany. Florence. ITA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 174, n° 1, 2011) |
| Pagination : | 63-71 |
| Langues: | Anglais |
| Mots-clés : | Court terme ; Facteur associé ; Association ; Santé environnementale ; Pollution atmosphérique ; Facteur risque ; Hospitalisation ; Résultat ; Epidémiologie ; Italie ; Europe ; Cardiopathie coronaire |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 8R0x989F. Diffusion soumise à autorisation]. Air pollutant levels have been widely associated with increased hospitalizations and mortality from cardiovascular disease. In this study, the authors focused on pollutant levels and triggering of acute myocardial infarction (AMI). Data on AMI hospitalizations, air quality, and meteorologic conditions were collected in 6 urban areas of Tuscany (central Italy) during 2002-2005. Levels of particulate matter with an aerodynamic diameter<=10 mum (PM10) (range of 4-year mean values, 28.15-40.68 mug/m3), nitrogen dioxide (range, 28.52-39.72 mug/m3), and carbon monoxide (range, 0.86-1.28 mg/m3) were considered, and increases of 10 mug/m3 (0.1 mg/m3 for carbon monoxide) were analyzed. A time-stratified case-crossover approach was applied. Area-specific conditional regression models were fitted, adjusting for time-dependent variables. Stratified analyses and analyses in bipollutant models were performed. Pooled estimates were derived from random-effects meta-analyses. Among 11,450 AMI hospitalizations, the meta-analytical odds ratio at lag2 (2-day lag) was 1.013 (95% confidence interval (CI) : 1.000,1.026) for PM10,1.022 (95% CI : 1.004,1.041) for nitrogen dioxide, and 1.007 (95% CI : 1.002,1.013) for carbon monoxide. More susceptible subgroups were elderly persons (age>75 years), females, and older patients with hypertension and chronic obstructive pulmonary disease. This study adds to evidence for a short-term association between air pollutants and AMI onset, also evident at low pollutant levels, suggesting a need to focus on more vulnerable subjects. |
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