Résumé :
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[BDSP. Notice produite par INIST-CNRS 2vR0x38G. Diffusion soumise à autorisation]. In a longitudinal cohort study of 1,248 nonpregnant young women recruited from three Pittsburgh, Pennsylvania, health clinics in 1998-2000, the authors investigated risk factors associated with vaginal acquisition of group B Streptococcus (GBS). Rectal and vaginal swabs for GBS culture and demographic and behavioral interview data were obtained from the women at enrollment and at three 4-month intervals. Cox proportional hazards models were used to evaluate risk factors for GBS acquisition among the 1,089 women with follow-up data. At enrollment, 365 (29.2%) of the 1,248 study participants were vaginally colonized with GBS. Of 767 women who were GBS-negative at enrollment, 344 (44.9%) acquired vaginal GBS colonization during follow-up. The following factors were independently associated with vaginal acquisition of GBS at the 0.05 significance level : African-American race (hazard ratio (HR)=1.5,95% confidence interval (Cl) : 1.2,1.9), having multiple sex partners during the past 4 months (HR=1.7,95% CI : 1.1,2.5), having frequent sexual intercourse during the past 4 months (HR=1.5,95% CI : 1.1,2.2), and having sexual intercourse within the 5 days prior to the follow-up visit (HR=1.6,95% CI : 1.3,2.0). These results show that sexual activity is an important risk factor for vaginal acquisition of GBS.
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