Résumé :
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[BDSP. Notice produite par INIST i9R0x32y. Diffusion soumise à autorisation]. Objectives. This population-based study examined the effect of all major congenical anomalics on the mortality of White and Black infants by infant ses, birthweight, gestational age, and lethality of the anomaly. The study also determined the total contribution of anomatics to infant inortality Methods. California Birth Defects Monitoring Program data were merged with linked birth-death files for 278646 singleton non-Hispanie White and Diack infants born in 1983 through 1986. Malformed infants were compared with nonmalformed infants to determine the effect of anomalies on mortality. Results. The presence of any congenital anomaly increased mortality 9.0-fold (95% CI=73.11.13 for Black infants and 17.8-fold (95% CI=16.2,19.8) for White infants Even "non-ltehal" anomalies increased mortality up to 8.9-fold Overnil, anomalics coniributed to 33% of White infant deaths, to 19% of Black infant deaths, and to over 60% of deaths among Black and White neonates weighing over 1499 g. Conclusions. The contribation of congenital anomalies to mortality of both low (
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