| Titre : | Two outbreaks of multidrug-resistant Salmonella serotype Typhimurium DT104 infections linked to raw-milk cheese in Northem California. (1999) |
| Auteurs : | S.H. CODY ; S.L. ABBOTT ; A.A. MARFIN ; J.C. MOHLE-BOETANI ; K. Robbins ; B. SCHULZ ; D.J. VUGIA ; P. WAGNER ; Division of Communicable Disease Control. California Department of Health Services. Berkeley. USA ; Public Health Department. Santa Clara Valley Health and Hospital System. San Jose. CA. USA |
| Type de document : | Article |
| Dans : | JAMA - Journal of the american medical association (vol. 281, n° 19, 1999) |
| Pagination : | 1805-1810 |
| Langues: | Anglais |
| Mots-clés : | Salmonellose ; Bactériose ; Infection ; Homme ; Etats Unis ; Amérique ; Etiologie ; Alimentation ; Bactérie ; Facteur risque ; Appareil digestif [pathologie] ; Amérique du Nord |
| Résumé : | [BDSP. Notice produite par INIST R0xuDcPm. Diffusion soumise à autorisation]. Context Salmonella serotype Typhimurium definitive type 104 (DT104), with resistance to 5 drugs (ampicillin, chloramphenicol, streptomycin, sulfonamides, and tetracycline), has emerged as the most common multidrug-resistant Salmonella strain in the United States. However, illnesses resulting from this strain have not been associated definitively with a source in this country. Objective To determine the source of 2 outbreaks of Salmonella Typhimurium DT104. Design Matched case-control study conducted between March 24 and April 5,1997 (outbreak 1), enhanced surveillance for new cases dating from February 1,1997 (outbreak 2), and environmental and laboratory investigations. Setting and Participants The case-control study included residents of 2 adjacent counties in northern California infected with the outbreak strain of Salmonella Typhimurium var Copenhagen and age-matched controls. For enhanced surveillance, a case was defined as Salmonella Typhimurium infection in a person exposed to fresh Mexican-style cheese. Main Outcome Measures Risk factors for infection and source of implicated food. Results Outbreak 1 peaked in February 1997 ; 31 patients were confirmed by culture as having Salmonella Typhimurium var Copenhagen infection, isolates of which showed indistinguishable pulsed-field gel electrophoresis (PFGE) patterns. The outbreak strain was phage type DT104 with the 5-drug resistance pattern. (...) |
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