Titre :
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Proceedings of Health Conference'97 - Great Lakes/St. Lawrence. Motor function in aging Great Lakes fisheaters. (1999)
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Auteurs :
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S.L. SCHANTZ ;
Christopher-T DE ROSA, éd. ;
J.C. GARDINER ;
D.M. GASIOR ;
Andrew-P GILMAN, éd. ;
H.E.B. HUMPHREY ;
R.J. MCCAFFREY ;
Zemoria-A ROSEMOND, éd. ;
A.M. SWEENEY ;
Agency for Toxic Substances and Disease Registry. Us Department of Health and Human Services. Atlanta. GA. USA ;
Department of Epidemiology. College of Human Medicine. Michigan State University. East Lansing. MI. USA ;
Health Canada. CAN ;
Health Conference'97 - Great Lakes/St. Lawrence. (12/05/1997; Montréal. PQ. CAN)
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Type de document :
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Article
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Dans :
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Environmental research (vol. 80, n° 2, 1999)
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Pagination :
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S46-S56
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Langues:
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Anglais
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Mots-clés :
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PCB
;
Etude comparée
;
Taux
;
Sang
;
Vieillissement
;
Trouble motricité
;
Personne âgée
;
Homme
;
Sexe
;
Age
;
Poisson
;
Aliment
;
Consommation alimentaire
;
Habitude alimentaire
;
Pollution eau
;
Système nerveux [pathologie]
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Résumé :
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[BDSP. Notice produite par INIST E7R0x686. Diffusion soumise à autorisation]. Exposure to contaminants in Great Lakes fish has been linked to impaired neuropsychological functioning in children, but neurological function of exposed adults has not been evaluated. This report describes a cross-sectional analysis of the effects of PCB/DDE exposure from contaminated fish on fine motor function in older adults. The subjects were 50-90-year-old Michigan residents who were members of a previously established study cohort. Fisheaters ate 24 lbs or more of sport-caught Lake Michigan fish/year at the time they were originally recruited in 1980-1982. Age-and sex-matched non-fisheaters ate 6 or fewer lbs/year. Outcome measures were scores on the Static Motor Steadiness Test (SMST) and Grooved Pegboard Test (GPT). PCB/DDE exposure was determined through serum analyses performed at the time of recruitment into the present study in 1993-1995. Because of the high correlation between serum PCB and DDE levels in this sample (Spearman r=0.64, P<0.0001), the effects of the two contaminants were assessed jointly using a single derived exposure variable : Low=both PCB and DDE at or below the medians of their respective distributions, intermediate=PCB and/or DDE in the third quartile, and high=PCB and/or DDE in the upper quartile. In unadjusted analyses, high exposure to PCBs/DDE was associated with significantly poorer performance on the GPT (P=0.03). (...)
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