Résumé :
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[BDSP. Notice produite par INIST 99ZR0xP4. Diffusion soumise à autorisation]. The relation between caffeine intake and menstrual function was examined in 403 healthy premenopausal women who belonged to Kaiser Permanente Medical Care Program in 1990-1991. A telephone interview collected information about caffeinated beverage intake as well as other lifestyle, demographic, occupational, and environmental factors. Subjects collected daily urine samples and completed a daily diary for an average of five menstrual cycles. Metabolites of estrogen and progesterone were measured in the urine, each cycle was characterized as anovulatory or ovulatory, and a probable day of ovulation was selected when appropriate. Logistic regression and repeated measures analyses were performed on menstrual parameters. Women whose caffeine consumption was heavy (>300 mg of caffeine per day) had less than a third of the risk for long menses (>8 days) compared with women who did not consume caffeine (adjusted odds ratio=0.30,95% confidence interval 0.14-0.66). Those whose caffeine consumption was heavy also had a doubled risk for short cycle length (<24 days) (adjusted odds ratio=2.00,95% confidence interval 0.98-4.06) ; this association was also evident in those whose caffeine consumption was heavy who did not smoke (adjusted odds ratio=2.11,95% confidence interval 1.03-4.33). (...)
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