| Titre : | Pregnancy, body weight and human immunodeficiency virus infection in African women : a prospective cohort study in Kigali (Rwanda), 1992-1994. (1998) |
| Auteurs : | J. LADNER ; Katia Castetbon ; M. CHAULIAC ; Francois Dabis ; A. DE CLERCQ ; E. KARITA ; V. LEROY ; M. NYIRAZIRAJE ; P. VAN DE PERRE ; Aids Reference Laboratory. National Aids Control Programme. Kigali. RWA ; Department of Gynaecology and Obstetrics. Chk. FRA ; Inserm U 330. Bordeaux. FRA ; Pregnancy and Hiv Study Group Ege. INC |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 27, n° 6, 1998) |
| Pagination : | 1072-1077 |
| Langues: | Anglais |
| Mots-clés : | Sida ; Virose ; Infection ; Grossesse ; Postpartum ; Poids corporel ; Modification ; Epidémiologie ; Facteur risque ; Homme ; Femme ; Rwanda ; Afrique ; Immunopathologie |
| Résumé : | [BDSP. Notice produite par INIST R0xCUWF7. Diffusion soumise à autorisation]. Objective To study the relationship between human immunodeficiency virus (HIV) infection and body weight in African women during and after pregnancy. Methods A prospective cohort study was initiated at the Centre Hospitalier de Kigali in July 1992. Every woman seen at the antenatal clinic and with a gestational age of<28 weeks was offered HIV-1 antibody testing. Comparable numbers of HIV-infected (HIV+) and uninfected (HIV-) women were recruited. At inclusion, socio-demographic characteristics and self-reported pre-pregnancy weight were recorded ; height and weight were measured. Each woman enrolled had a monthly follow-up until 9 months after delivery, with a clinical examination including weighing. Three anthropometric indices were used to answer the study objectives : weight, body mass index (BMI), and pregnancy balance. Results As of April 1994,101 HIV+and 106 HIV-women were followed until 5 months after delivery. Weight and BMI during pregnancy were lower in HIV+women than in HIV-women. After delivery, weight and BMI gains were significantly lower in HIV+women. Until 5 months after delivery, the mean weight variation was - 2.2 kg (standard deviation [SD]=5.9 kg) in HIV+women and+0.2 kg (SD=6.6 kg) in HIV-women (P=0.007) in comparison to pre-pregnancy weight. Comparisons of the slopes of the weight curves did not show statistical differences throughout the pregnancy, but it did during the post-partum period (P=0.02). (...) |
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