| Titre : | Exposure to nitrogen dioxide and the occurrence of bronchial obstruction in children below 2 years. (1998) |
| Auteurs : | P. MAGNUS ; L.S. BAKKETEIG ; G. BECHER ; G. BOTTEN ; K.C.L. CARLSEN ; K.H. CARLSEN ; J. KONGERUD ; P. NAFSTAD ; L. OIE ; S.O. SAMUELSEN ; Department of Population Health Sciences. National Institute of Public Health. Po Box 4404 Torshov. Oslo. NOR |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 27, n° 6, 1998) |
| Pagination : | 995-999 |
| Langues: | Anglais |
| Mots-clés : | Asthme ; Bronche ; Pollution atmosphérique ; Circulation routière ; Epidémiologie ; Facteur risque ; Enfant ; Homme ; Norvège ; Europe ; Appareil respiratoire [pathologie] ; Bronchopneumopathie obstructive |
| Résumé : | [BDSP. Notice produite par INIST hVpOVR0x. Diffusion soumise à autorisation]. Background The objective of the investigation was to test the hypothesis that exposure to nitrogen dioxide (NO2) has a causal influence on the occurrence of bronchial obstruction in children below 2 years of age. Methods A nested case-control study with 153 one-to-one matched pairs was conducted within a cohort of 3754 children born in Oslo in 1992/93. Cases were children who developed >=2 episodes of bronchial obstruction or one episode lasting>4 weeks. Controls were matched for date of birth. Exposure measurements were performed in the same 14-day period within matched pairs. The NO2 exposure was measured with personal samplers carried close to each child and by stationary samplers outdoors and indoors. Results Few children (4.6%) were exposed to levels of NO2 >= 30 mug/m3 (average concentration during a 14-day period). In the 153 matched pairs, the mean level of NO2 was 15.65 mug/m3 ( 0.60, SE) among cases and 15.37 ( 0.54) among controls (paired t=0.38, P=0.71). Conclusions The results suggest that NO2 exposure at levels observed in this study has no detectable effect on the risk of developing bronchial obstruction in children below 2 years of age. |
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