| Titre : | Diphtheria antitoxin levels in the 14-30-year age group in Italy. (1998) |
| Auteurs : | I. MASTROENI ; S. BAGNOD ; S. BOCCHINI ; C. CIAPETTI ; G.M. FARA ; A.M. PATTI ; A.L. SANTI ; N. VESCIA ; Institute of Hygiene'La Sapienza'University of Rome. ITA |
| Type de document : | Article |
| Dans : | European journal of epidemiology (vol. 14, n° 7, 1998) |
| Pagination : | 683-686 |
| Langues: | Anglais |
| Mots-clés : | Vaccin antidiphtérique ; Vaccination ; Diphtérie ; Bactériose ; Infection ; Examen sérologique ; Taux ; Epidémiologie ; Evaluation ; Jeune adulte ; Homme ; Italie ; Europe |
| Résumé : | [BDSP. Notice produite par INIST ilV87R0x. Diffusion soumise à autorisation]. In order to verify diphtheria immunity a seroepidemiological survey was performed in 1996-1997. Serum samples were obtained from 501 subjects 14 years old, recruited at 8 schools in Rome, and from 490 subjects 20-30 years old recruited from 15 Italian regions. Serum diphtheria antitoxin was titrated using the Vero cell assay. The minimum protection level of antitoxin was set at 0.01 IU ml-1. The results show that the younger population have a good immunity to diphtheria while a large proportion of young adults is devoid of protective levels of diphtheria antitoxin. Out of the 501 subjects 14 years old. 495 (98.8%) had a diphtheria antitoxin titre >= 0.01 IU ml-1. Only 6 (1.2%) teenagers were susceptible. Out of the 490 subjects 20-30 years old, 109 (22.2%) were susceptible. 381 (77.8%) had a diphtheria antitoxin titre >= 0.01 IU ml-1. The data stress for booster immunization at the end of junior high school. |

