Résumé :
|
[BDSP. Notice produite par INIST R0x1hARY. Diffusion soumise à autorisation]. Objective-To assess the risk to human health of the plant bracken (Pteridium sp). Design-An evaluation of studies of human and animal populations exposed to bracken, together with a review of expert reports and advice to the public. Main results-Bracken induced disease has been demonstrated in animals in both laboratory and field studies. Depending on the species, diseases in animals associated with the plant have included : cancers of the alimentary and urogenital tract, lung and breast ; haematuria ; retinal degeneration ; and, thiamine deficiency. Potential exposure of human populations is through : food either directly (people in some parts of the world eat bracken as a traditional dish) or indirectly by consuming animals fed on bracken ; milk ; water ; inhalation and ingestion of spores ; and insect vectors. Four studies of human populations (two analytical and two observational) failed to assess adequately confounding factors and other sources ofbias, so that conclusions about a risk to human health from bracken cannot firmly be drawn. Establishing exposure is also extremely difficult in populations (such as the United Kingdom) where direct consumption of bracken is rare. Conclusion-Bracken is a common plant worldwide. It is toxic to many animal species and to several organ systems. There is no tumour (or other disease) that is pathognomic of exposure in animals, though cancers ofthe alimentary and urogenital tract seem to be the most commonly associated. (...)
|