| Titre : | Evaluating cluster alarms : A space-time scan statistic and brain cancer in Los Alamos, New Mexico. (1998) |
| Auteurs : | M. KULLDORFF ; W.F. ATHAS ; E.J. FEUER ; C.R. KEY ; B.A. Miller ; Division of Cancer Control and Population Sciences. National Cancer Institute. Bethesda Md. USA |
| Type de document : | Article |
| Dans : | American journal of public health (vol. 88, n° 9, 1998) |
| Pagination : | 1377-1380 |
| Langues: | Anglais |
| Mots-clés : | Cancer ; Cerveau ; Epidémiologie ; Incidence ; Evolution ; Homme ; Etats Unis ; Amérique du Nord ; Amérique ; Système nerveux [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST 2RlR0xhQ. Diffusion soumise à autorisation]. Objectives. This article presents a space-time scan statistics, useful for evaluating space-time cluster alarms, and illustrates the methods on a recent brain cancer cluster alarm in Los Alamos, NM. Methods. The space-time scan statistic accounts for the preselection bias and multiple testing inherent in a cluster alarm. Confounders and time trends can be ajusted for. Results. The observed excess of brain cancer in Los Alamos was not statistically significant Conclusions. The space-time scan statistic is useful as a screening tool for evaluating which cluster alarms merit further investigation and which clusters are probably chances occurrences. |

