Titre :
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Evaluating cluster alarms : A space-time scan statistic and brain cancer in Los Alamos, New Mexico. (1998)
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Auteurs :
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M. KULLDORFF ;
W.F. ATHAS ;
E.J. FEUER ;
C.R. KEY ;
B.A. MILLER ;
Division of Cancer Control and Population Sciences. National Cancer Institute. Bethesda Md. USA
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Type de document :
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Article
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Dans :
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American journal of public health (vol. 88, n° 9, 1998)
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Pagination :
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1377-1380
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Langues:
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Anglais
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Mots-clés :
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Cancer
;
Cerveau
;
Epidémiologie
;
Incidence
;
Evolution
;
Homme
;
Etats Unis
;
Amérique du Nord
;
Amérique
;
Système nerveux [pathologie]
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Résumé :
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[BDSP. Notice produite par INIST 2RlR0xhQ. Diffusion soumise à autorisation]. Objectives. This article presents a space-time scan statistics, useful for evaluating space-time cluster alarms, and illustrates the methods on a recent brain cancer cluster alarm in Los Alamos, NM. Methods. The space-time scan statistic accounts for the preselection bias and multiple testing inherent in a cluster alarm. Confounders and time trends can be ajusted for. Results. The observed excess of brain cancer in Los Alamos was not statistically significant Conclusions. The space-time scan statistic is useful as a screening tool for evaluating which cluster alarms merit further investigation and which clusters are probably chances occurrences.
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