| Titre : | Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk. (1998) |
| Auteurs : | B.C. HEROLD ; S. BOYLE-VAVRA ; R.S. DAUM ; R.E. GASKIN ; L.C. IMMERGLUCK ; D.S. LAUDERDALE ; C.D. LEITCH ; M.C. MARANAN ; Department of Pediatrics. The University of Chicago Hospitals. Chicago. USA |
| Type de document : | Article |
| Dans : | JAMA - Journal of the american medical association (vol. 279, n° 8, 1998) |
| Pagination : | 593-598 |
| Langues: | Anglais |
| Mots-clés : | Bactérie ; Communauté ; Prévalence ; Enfant ; Homme ; Bactériose ; Infection ; Médicament antibiotique |
| Résumé : | [BDSP. Notice produite par INIST Bl5R0xZE. Diffusion soumise à autorisation]. Context. - Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infections in children have occurred primarily in individuals with recognized predisposing risks. Community-acquired MRSA infections in the absence of identified risk factors have been reported infrequently. Objectives. To determine whether community-acquired MRSA infections in children with no identified predisposing risks are increasing and to define the spectrum of disease associated with MRSA isolation. Design. - Retrospective review of medical records. Patients. - Hospitalized children with S aureus isolated between August 1988 and July 1990 (1988-1990) and between August 1993 and July 1995 (1993-1995). Setting. - The University of Chicago Children's Hospital. Main Outcome Measures. - Prevalence of community-acquired MRSA over time, infecting vs colonizing isolates, and risk factors for disease. Results. - The number of children hospitalized with community-acquired MRSA disease increased from 8 in 1988-1990 to 35 in 1993-1995. Moreover, the prevalence of community-acquired MRSA without identified risk increased from 10 per 100000 admissions in 1988-1990 to 259 per 100000 admissions in 1993-1995 (P<. 001), and a greater proportion of isolates produced clinical infection. The clinical syndromes associated with MRSA in children without identified risk were similar to those associated with community-acquired methicillin-susceptible S aureus. (...) |
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