Titre :
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Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk. (1998)
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Auteurs :
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B.C. HEROLD ;
S. BOYLE-VAVRA ;
R.S. DAUM ;
R.E. GASKIN ;
L.C. IMMERGLUCK ;
D.S. LAUDERDALE ;
C.D. LEITCH ;
M.C. MARANAN ;
Department of Pediatrics. The University of Chicago Hospitals. Chicago. USA
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Type de document :
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Article
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Dans :
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JAMA - Journal of the american medical association (vol. 279, n° 8, 1998)
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Pagination :
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593-598
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Langues:
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Anglais
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Mots-clés :
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Bactérie
;
Communauté
;
Prévalence
;
Enfant
;
Homme
;
Bactériose
;
Infection
;
Médicament antibiotique
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Résumé :
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[BDSP. Notice produite par INIST Bl5R0xZE. Diffusion soumise à autorisation]. Context. - Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infections in children have occurred primarily in individuals with recognized predisposing risks. Community-acquired MRSA infections in the absence of identified risk factors have been reported infrequently. Objectives. To determine whether community-acquired MRSA infections in children with no identified predisposing risks are increasing and to define the spectrum of disease associated with MRSA isolation. Design. - Retrospective review of medical records. Patients. - Hospitalized children with S aureus isolated between August 1988 and July 1990 (1988-1990) and between August 1993 and July 1995 (1993-1995). Setting. - The University of Chicago Children's Hospital. Main Outcome Measures. - Prevalence of community-acquired MRSA over time, infecting vs colonizing isolates, and risk factors for disease. Results. - The number of children hospitalized with community-acquired MRSA disease increased from 8 in 1988-1990 to 35 in 1993-1995. Moreover, the prevalence of community-acquired MRSA without identified risk increased from 10 per 100000 admissions in 1988-1990 to 259 per 100000 admissions in 1993-1995 (P<. and a greater proportion of isolates produced clinical infection. the syndromes associated with mrsa in children without identified risk were similar to those community-acquired methicillin-susceptible s aureus.>
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