Titre : | Influence of delay on survival in patients with breast cancer : a systematic review. (1999) |
Auteurs : | M.A. RICHARDS ; P. LITTLEJOHNS ; S.B. LOVE ; A.J. RAMIREZ ; A.M. WESTCOMBE |
Type de document : | Article |
Dans : | Lancet (The) (vol. 353, n° 9159, 1999/04/03) |
Pagination : | 1119-1126 |
Langues: | Anglais |
Mots-clés : | Délai ; REPORT SOINS ; Accès soins ; Cancer ; Sein ; Enquête ; Survie |
Résumé : | Background : Most patients with breast cancer are detected after symptoms occur rather than through screening. The impact on survival of delays between the onset of symptoms and the start of treatment is controversial and cannot be studied in randomised controlled trials. We did a systematic review of observational studies (worldwide) of duration of symptoms and survival. (...) Interpretation : Delays of 3-6 months are associated with lower survival. These effects cannot be accounted for by lead-time bias. Efforts should be made to keep delays by patients and providers to a minimum. |