Résumé :
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[BDSP. Notice produite par INIST HBR0x98A. Diffusion soumise à autorisation]. In a 6-year prospective study, the authors examined the relation between diet and incident colon cancer among 32,051 non-Hispanic white cohort members of the Adventist Health Study (California, 1976-1982) who, at baseline, had no documented or reported history of cancer. The risk of colon cancer was determined from proportional hazards regression with adjustment for age and other covariates. The authors found a positive association with total meat intake (risk ratio (RR) for >=1 time/week vs. no meat intake=1.85,95% confidence interval (Cl) 1.19-2.87 ; p for trend=0.01) and, among subjects who favored specific types of meat, positive associations with red meat intake (RR for >=1 time/week vs. no red meat intake=1.90,95% Cl 1.16-3.11 ; p for trend=0.02) and white meat intake (RR for >=1 time/week vs. no white meat intake=3.29,95% Cl 1.60-6.75 ; p for trend=0.006). An inverse association with legume intake (RR for>2 times/week vs.<1 time/week=0.53,95% Cl 0.33-0.86 ; p for trend=0.03) was observed. Among men, a positive association with body mass index was observed (relative to the RR for tertile III (>25.6 kg/m2) vs. tertile I (<22.5 kg/m2)=2.63,95% Cl 1.12-6.13 ; p for trend=0.05). A complex relation was identified whereby subjects exhibiting a high red meat intake, a low legume intake, and a high body mass experienced a more than threefold elevation in risk relative to all other patterns based on these variables. (...)
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