| Titre : | Dental amalgam and multiple sclerosis : a case-control study in Montreal, Canada. (1998) |
| Auteurs : | D. BANGSI ; S. CICCOCIOPPO ; S. DUCIC ; P. GHADIRIAN ; D. KREWSKI ; E. MCMULLEN ; R. MORISSET ; Department of Microbiology. Hôtel-Dieu Pavilion. Chum. Montreal Quebec. CAN ; Department of Social and Preventive Medicine. Faculty of Medicine. University of Montreal. Montreal Quebec. CAN ; Epidemiology Research Unit. Research Center. Hôtel-Dieu Pavilion. Chum. Montreal Quebec. CAN |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 27, n° 4, 1998) |
| Pagination : | 667-671 |
| Langues: | Anglais |
| Mots-clés : | Sclérose plaque ; Mercure ; Carie dentaire ; Epidémiologie ; Facteur risque ; Homme ; Canada ; Amérique du Nord ; Amérique ; Système nerveux [pathologie] ; Stomatologie ; Dent [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST bR0xOTBJ. Diffusion soumise à autorisation]. Background The aetiology of multiple sclerosis (MS) remains poorly understood. Dental amalgams containing mercury have recently been suggested as a possible risk factor for MS. Methods In a case-control study conducted between 1991 and 1994, we interviewed a total of 143 MS patients and 128 controls, to obtain information on socio-demographic characteristics and the number of dental amalgams and the time since installation based on dentists'records. Results Neither the number nor the duration of exposure to amalgams supported an increased risk of MS. After adjustment for age, sex, smoking, and education those who had more than 15 fillings had an odds ratio (OR) of 2.57 (95% CI : 0.78-8.54) compared to those who had none ; for individuals whose first amalgam was inserted more than 15 years prior to the study, we found an OR of 1.34 (95% Cl : 0.38-4.72). Conclusions Although a suggestive elevated risk was found for those individuals with a large number of dental amalgams, and for a long period of time, the difference between cases and controls was not statistically significant. |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact