| Titre : | Urbanization and childhood leukaemia in Taiwan. (1998) |
| Auteurs : | C.Y. LI ; R.S. LIN ; C.H. LIN |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 27, n° 4, 1998) |
| Pagination : | 587-591 |
| Langues: | Anglais |
| Mots-clés : | Leucémie ; Densité population ; Infection ; Etude comparée ; Epidémiologie ; Incidence ; Facteur risque ; Evolution ; Enfant ; Homme ; Taiwan ; Asie |
| Résumé : | [BDSP. Notice produite par INIST R0xEjiOg. Diffusion soumise à autorisation]. Background In the 1980s socioeconomic development was dramatically rapid in the urbanized municipalities of Taiwan due to a prospering economy. This study addressed the question : Could differences in the incidence of childhood leukaemia (age<15) be demonstrated between urban and rural communities in Taiwan between 1981 and 1990 ? Methods The log-linear regression model was used to assess the effects of age, level of urbanization, and calendar year on the variation of childhood leukaemia incidence rates between 1981 and 1990. Results Between 1981 and 1990, the overall incidence rate of childhood leukaemia increased by 20% (rate ratio (RR)=1.2,95% CI : 1.0-1.5). As compared to rural areas, metropolitan regions showed a significantly higher incidence rate during the study period (RR=1.3,95% CI : 1.1-1.6). This urban-rural difference was particularly notable among children<5 years old (RR=1.5,95% CI : 1.2-1.9). Dose-response analysis further indicated that risk of childhood leukaemia was monotonically associated with levels of urbanization. The significant gradient in the risk of childhood leukaemia with urbanization was contributed solely by children in the 0-4 years age group. Conclusions We noticed a relationship between urbanization and risk of leukaemia in children. (...) |
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