Résumé :
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[BDSP. Notice produite par INIST R0xNOWkC. Diffusion soumise à autorisation]. Background Mortality in specified clinical populations has often been regarded as a measure of treatment effectiveness. This study examined time trends in mortality of drug addicts in the UK notified to the Home Office over a 27-year period. Methods The study was a longitudinal analysis of routine mortality data of a population of newly notified addicts from 1967 to 1993. Altogether, 92 802 addicts were newly notified during the study period, and they accounted for 687 673 person-years of observation. The main outcome measures were age-specific all-causes mortality ; drug-related mortality : and age-and sex-specific standardized mortality ratios (SMR) 1967-1993. Results There were significant differences in death rates between the periods 1967-1976 (19/1000 person-years) and 1984-1993 (10.5/1000 person-years). Excess deaths were significantly higher among the 1967-1976 cohorts than in the 1984-1993 cohorts (SMR ratio=1.80,95% CI : 1.64-1.97). The majority of deaths were drug-related, with those aged<45 years more likely to die of a drug-related cause than those older (OR=6.29,95% CI : 4.97-7.96). Conclusions It appears that service provision has some impact on all-causes mortality among opiate addicts. As services improved, there was a corresponding decline in mortality rates during the study period. Further preventive measures, however, should be devised to reduce drug-related deaths.
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