| Titre : | Sudden infant death syndrome : Risk factor profiles for distinct subgroups. (1998) |
| Auteurs : | U. KOHLENDORFER ; S. KIECHL ; W. SPERL ; Department of Pediatrics. University Hospital of Innsbruck. Innsbruck. ATR |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 147, n° 10, 1998) |
| Pagination : | 960-968 |
| Langues: | Anglais |
| Mots-clés : | Mort subite ; Mortalité postnéonatale ; Létalité ; Epidémiologie ; Facteur risque ; Nourrisson ; Homme ; Autriche ; Europe |
| Résumé : | [BDSP. Notice produite par INIST HR0xX2RJ. Diffusion soumise à autorisation]. The authors investigated risk profiles of sudden infant death syndrome (SIDS) as a function of age at death. A case-control study carried out in the Tyrol region of Austria enrolled 99 infants who died of SIDS between 1984 and 1994 and 136 randomly selected controls. Early and late SIDS (<120 days of age vs. 20 days) were defined according to the clear-cut bimodal age-at-death distribution. Inadequate antenatal care, low parental social and educational level, and the prone sleeping position were risk conditions that applied to both early and late SIDS. A marked seasonal variation (winter preponderance) was the most outstanding feature of late SIDS. A gestational age of<37 weeks (odds ratio (OR)=8.4,95% confidence interval (Cl) 2.6-26.0), repeated episodes of apnea (OR=5.7,95% CI 1.2-27.0), low birth weight (<2,500 g) (OR=3.4,95% Cl 1.1-11.0), a family history of sudden infant death (OR=2.9,95% Cl 1.1-7.5), and maternal smoking during pregnancy (OR=2.2,95% Cl 1.0-4.5) were associated with early SIDS. This study identified two distinct subgroups of SIDS infants characterized by different risk conditions and ages at death. These results underline a multiple-cause hypothesis for SIDS etiology which involves a genetic predisposition, immaturity in the first months of life, and environmental factors acting at various ages. |
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