| Titre : | Meta-analysis of coffee consumption and risk of colorectal cancer. (1998) |
| Auteurs : | E. GIOVANNUCCI |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 147, n° 11, 1998) |
| Pagination : | 1043-1052 |
| Langues: | Anglais |
| Mots-clés : | Cancer ; Rectum ; Café ; Consommation ; Epidémiologie ; Facteur risque ; Homme ; Appareil digestif [pathologie] ; Intestin [pathologie] ; Alimentation ; Côlon |
| Résumé : | [BDSP. Notice produite par INIST zR0x67vk. Diffusion soumise à autorisation]. Several studies have found that coffee consumption is related to a lower risk of colorectal cancer, but results have not been consistent. Thus, a meta-analysis of the published articles was conducted to examine this relation. Because of the various ways data were collected and analyzed, a "semiquantitative" approach that compared the high versus the low category of intake for each study was used. The combined results from 12 case-control studies showed an inverse association between coffee consumption and risk of colorectal cancer (pooled relative risk (estimated by odds ratio) for high vs. low category of coffee consumption (RR)=0.72,95% confidence interval (Cl) 0.61-0.84) ; the findings were similar in population-based and hospital-based case-control studies. Five cohort studies did not support an association (pooled RR=0.97,95% Cl 0.73-1.29). The combined results of all studies were driven largely by the case-control studies, which comprised 85 percent of the cases (RR=0.76,95% Cl 0.66-0.89). The lower risk of colorectal cancer among substantial coffee drinkers was observed in studies from Asia, Northern and Southern Europe, and North America. (...) |
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