| Titre : | Relation of smoking to the incidence of Age-related maculopathy : The Beaver Dam Eye study. (1998) |
| Auteurs : | R. Klein ; B.E.K. KLEIN ; S.E. MOSS ; Department of Ophthalmology and Visual Sciences. University of Wisconsin Medical School. Madison WI. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 147, n° 2, 1998) |
| Pagination : | 103-110 |
| Langues: | Anglais |
| Mots-clés : | Tabagisme ; Age ; Epidémiologie ; Facteur risque ; Incidence ; Homme ; Etats Unis ; Amérique du Nord ; Amérique ; Oeil [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST kR0xB4BP. Diffusion soumise à autorisation]. To date, a number of reports have been published on the relation of cigarette smoking to age-related maculopathy, an important cause of blindness in the United States. However, few studies have examined the relation between smoking and the incidence of age-related maculopathy. In this report, the authors examine this association in persons aged 43-86 years (n=3,583) at baseline who were participants in the baseline examination and 5-year follow-up of the Beaver Dam Eye Study, Beaver Dam, Wisconsin (1988-1990 and 1993-1995). Exposure data on cigarette smoking were obtained from questions about present and past smoking, duration of smoking, and the number of cigarettes smoked per day. Age-related maculopathy status was determined by grading stereoscopic color fundus photographs using the Wisconsin Age-related Maculopathy Grading System. After controlling for age, sex, vitamin supplement use, and beer consumption, men who smoked greater amounts of cigarettes were more likely to develop early age-related maculopathy (odds ratio (OR) per 10 pack-years smoked=1.06,95% confidence interval (Cl) 1.00-1.13, p=0.06) than men who had smoked less. This association was not observed in women. Men (OR=3.21,95% Cl 1.09-9.45) and women (OR=2.20,95% Cl 1.04-4. (...) |
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