| Titre : | Breast cancer clusters in the Northeast United States : A geographic analysis. (1997) |
| Auteurs : | M. KULLDORFF ; E.J. FEUER ; L.S. FREEDMAN ; B.A. MILLER ; Division of Cancer Prevention and Control. National Cancer Institute. Bethesda MD. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 146, n° 2, 1997) |
| Pagination : | 161-170 |
| Langues: | Anglais |
| Mots-clés : | Cancer ; Sein ; Epidémiologie ; Etats Unis ; Amérique du Nord ; Amérique ; Homme ; Létalité ; Méthodologie ; Facteur risque ; Age ; Race ; Glande mammaire [pathologie] ; Milieu urbain |
| Résumé : | [BDSP. Notice produite par INIST 5R0x77pj. Diffusion soumise à autorisation]. High breast cancer mortality rates have been reported in the northeastern part of the United States, with recent attention focused on Long Island, New York. In this study, the authors investigate whether the high breast cancer mortality is evenly spread over the Northeast, in the sense that any observed clusters of deaths can be explained by chance alone, or whether there are clusters of statistical significance. Demographic data and age-specific breast cancer mortality rates for women were obtained for all 244 counties in 11 northeastern states and for the District of Columbia for 1988-1992. A recently developed spatial scan statistic is used, which searches for clusters of cases without specifying their size or location ahead of time, and which tests for their statistical significance while adjusting for the multiple testing inherent in such a procedure. The basic analysis is adjusted for age, with further analyses examining how the results are affected by incorporating race, urbanicity, and parity as confounding variables. There is a statistically significant and geographically broad cluster of breast cancer deaths in the New York City-Philadelphia, Pennsylvania, metropolitan area (p=0.0001), which has a 7.4% higher mortality rate than the rest of the Northeast. The cluster remains significant when race, urbanicity, and/or parity are included as confounding variables. (...) |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact