| Titre : | Diet and the risk of salivary gland cancer. (1997) |
| Auteurs : | P.L. Horn-Ross ; B.M. LJUNG ; M. MORROW ; Epidemiology Program. Northem California Cancer Center. Union City CA. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 146, n° 2, 1997) |
| Pagination : | 171-176 |
| Langues: | Anglais |
| Mots-clés : | Cancer ; Glande salivaire ; Epidémiologie ; Homme ; Alimentation ; Vitamine C ; Vitamine ; Antioxydant ; Cholestérol ; Lipide ; Fruit ; Légume ; Ration alimentaire ; Fibre alimentaire ; Stomatologie ; Etats Unis ; Amérique du Nord ; Amérique |
| Résumé : | [BDSP. Notice produite par INIST 5DR0xfFg. Diffusion soumise à autorisation]. Cancer of the major salivary glands is relatively rare, and little is known about its etiology. The only established risk factors are radiation exposure and a prior cancer. The role of diet in the development of salivary gland tumors has not been addressed previously. The results from a population-based case-control study conducted in the greater San Francisco-Monterey Bay area examining the association between dietary intake and salivary gland cancer risk are presented. Of 199 cases diagnosed with salivary gland tumors between 1989 and 1993,150 (75%) were interviewed. Nine cases were subsequently excluded based on review of pathology specimens. Of 271 controls identified through random-digit dialing and the Health Care Finance Administration files, 191 (70%) were interviewed. Eight cases and seven controls who over-or underreported dietary intake were excluded from analysis. Vitamin C intake of>200 mg/day compared with<100 mg/day was associated with a 60% decrease in salivary gland cancer risk (odds ratio (OR)=0.40,95% confidence interval (Cl) 0.22-0.70). Inverse associations observed for carotene, vitamin E, and fiber from fruits and vegetables were diminished when adjusted for vitamin C intake. Fiber from bean sources was associated with a 51% decrease in risk after adjusting for vitamin C intake (OR=0.49,95% Cl 0.26-0.92 for>1.4 g/day compared with<0.4 g/day). Cholesterol intake was associated with elevated risk (OR=1.67,95% Cl 1.2-2. (...) |
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