| Titre : | Prevalence of hepatitis and HIV infections and vaccination rates in patients entering the heroin-assisted treatment in Switzerland between 1994 and 2002. (2006) |
| Auteurs : | Miriam GERLICH ; Patrick GSCHWEND ; Alexander KRAMER ; REHM (Jürgen) : CAN. Center for Addiction and Mental Health. Toronto. ; Ambros UCHTENHAGEN ; Research Institute for Public Health and Addiction. Zürich. CHE ; University of Bielefeld. Department of Public Health Medicine. Bielefeld. DEU |
| Type de document : | Article |
| Dans : | European journal of epidemiology (vol. 21, n° 7, 2006) |
| Pagination : | 545-549 |
| Langues: | Anglais |
| Mots-clés : | Prévalence ; Sida ; Virose ; Infection ; Toxicomanie ; Toxicomane ; Homme ; Malade ; Héroïne ; Hépatite virale A ; Drogue synthèse ; Thérapeutique ; Hépatite virale B ; Suisse ; Europe ; VIH ; Rétrovirus ; Virus ; Prévention santé ; Vaccination ; Epidémiologie ; Appareil digestif [pathologie] ; Foie [pathologie] ; Immunopathologie ; Couverture vaccinale |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 6qR0xja3. Diffusion soumise à autorisation]. Background : Hepatitis C virus (HCV) remains very prevalent in injection drug users (IDUs). In spite of recommended vaccinations against hepatitis A virus (HAV) and hepatitis B virus (HBV), many IDUs remain susceptible to HAV and HBV. Study population and methods : Patients entering heroin-assisted treatment between 2000 and 2002 (N=210) were compared for infectious disease status with patients entering this treatment in 1998 (N=243) and between 1994 and 1996 (N=1035). Infection status was determined with the aid of questionnaires and blood tests for antibodies against HAV, HBV core antigen, HCV and HIV. Results : In the cohort 2000-2002 78.3% of the patients were HCV positive, 53.3% were HBV positive, 41.2% were HAV positive and 12.6% were HIV positive. In comparison to the cohorts entering the heroin-assisted treatment at an earlier time, there was a significant reduction of HBV and HAV infections, but not of HCV and HIV infections. 15.6% of the patients entering between 2000 and 2002 were vaccinated against HBV and 10.3% against HAV. 31.1% of patients at entrance were susceptible for HBV and 48.5% for HAV. In comparison to patients entering treatment in 1998 there was no significant increase in patients who were vaccinated against HBV. Conclusions : This data illustrates the need for improving HCV prevention and more consequent vaccination against HBV and HAV in IDUs. |
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