| Titre : | Lack of association between tea and cardiovascular disease in college alumni. Commentary : Nutrition. (2003) |
| Auteurs : | Howard-D SESSO ; Lenore ARAB ; Dora ILYASOVA ; I-Min LEE ; Yuko OGUMA ; Ralph-Sjr PAFFENBARGER ; Ulrike Peters ; Charles POOLE ; Div of Preventive Medicine. Department of Medicine. Brigham and Women's Hospital and Harvard Medical School. Boston. MA. USA |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 32, n° 4, 2003) |
| Pagination : | 527-535 |
| Langues: | Anglais |
| Mots-clés : | Thé ; Consommation alimentaire ; Epidémiologie ; Appareil circulatoire [pathologie] ; Homme |
| Résumé : | [BDSP. Notice produite par INIST-CNRS mfvabR0x. Diffusion soumise à autorisation]. Background : Epidemiological studies suggest that tea intake, a major dietary source of flavonoids, may be associated with a decreased risk of cardiovascular disease (CVD). Methods : We prospectively followed 17 228 subjects (mean age, 59.5 years) initially free of CVD and cancer from the College Alumni Health Study. Participants provided baseline self-reports of tea consumption (cups/day) and coronary risk factors. During a median follow-up of 15 years, there were 3372,2615, and 757 cases of CVD, coronary heart disease (CHD), and stroke, respectively, ascertained from either self-reports or death certificates. Results : Overall, the median level of tea consumption was 1 cup/day. Compared with participants consuming no tea, the multivariate relative risks (RR) of CVD for those drinking<1,1,2,3, and>=4 cups/day were 0.99,0.96,0.95,0.91, and 0.95, respectively (P, trend=0.19). The multivariate RR were 0.97,0.98,0.93,0.85, and 0.98 for CHD (P, trend=0.25), and 1.05,0.89,1.00,1.09, and 0.83 for stroke (P, trend=0.53). There was no evidence of effect modification. Changes in tea intake were assessed in a subgroup of 7730 men, with those continuing to drink tea having a non-significant 33% reduction in the risk of stroke. Conclusions : Tea intake, likely consumed as black tea, was not strongly associated with a reduced risk of CVD in this population of US college alumni. |
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